A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Reference Report

Reference
Citation Shaver, S.A., Riedl, C.A., Parkes, T.L., Sokolowski, M.B., Hilliker, A.J. (2000). Isolation of larval behavioral mutants in Drosophila melanogaster.  J. Neurogenet. 14(4): 193--205. (Export to RIS)
FlyBase ID FBrf0135854
Publication Type Research paper
PubMed ID 11342381
PubMed Abstract Genetic loci that influence behavior are often difficult to identify and localize in part due to the quantitative nature of behavioral phenotypes. Previous studies had found an association between pupal lethality and altered larval behavior for mutants of several genes. To facilitate the identification and localization of new mutants that influence larval foraging (movement in the presence of food) and general locomotion (movement in the absence of food) behaviors we identified and then screened a collection of strains carrying pupal-lethal mutations for alterations in these larval behaviors. When the lethal mutation segregated with the behavioral alteration this permitted the mapping of the behavioral locus. Nine new loci on the second chromosome were found to affect larval behavior. Of these, seven loci affected foraging and two affected locomotion. Analyses of these new loci will lead to further understanding of the mechanistic bases of larval behavior.
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Language of Publication English
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Publication Type Journal
Abbreviation J. Neurogenet.
Title Journal of Neurogenetics
Publication Year 1983-
ISBN/ISSN 0167-7063
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