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Citation
Lee, T., Luo, L. (2001). Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development.  Trends Neurosci. 24(5): 251--254.
FlyBase ID
FBrf0135958
Publication Type
Review
Abstract

We have modified an FLP/FRT-based genetic mosaic system to label either neurons derived from a common progenitor or isolated single neurons, in the Drosophila CNS. These uniquely labeled neurons can also be made homozygous for a mutation of interest within an otherwise phenotypically wild-type brain. Using this new mosaic system, not only can normal brain development be described with unprecedented single cell resolution, but also the underlying molecular mechanisms can be investigated by identifying genes that are required for these developmental processes.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Trends Neurosci.
    Title
    Trends in Neurosciences
    Publication Year
    1978-
    ISBN/ISSN
    0166-2236
    Data From Reference
    Genes (9)