|Citation||Costas, J., Valade, E., Naveira, H. (2001). Structural Features of the mdg1 Lineage of the Ty3/gypsy Group of LTR Retrotransposons Inferred from the Phylogenetic Analyses of Its Open Reading Frames. J. Mol. Evol. 53(3): 165--171. (Export to RIS)|
|Publication Type||Research paper|
|PubMed Abstract||The increasing amount of data generated in recent years has opened the way to exhaustive studies of the relationships among different members of the Ty3/gypsy group of LTR retrotransposons, a widespread group of eukaryotic transposable elements. Former research led to the identification of several independent lineages within this group. One of the worse represented of them is that of mdg1, integrated so far only by the Drosophila retrotransposons mdg1 and 412. Our exhaustive database searches indicate the existence of three other Drosophila members of this lineage. Two of them correspond to elements already known, namely, Stalker and blood, but the third one is a new element, which we have called Pilgrim. This element is well represented within the D. melanogaster genome, as revealed by our Southern blot analysis of different strains. The case of Stalker is particularly remarkable, since its phylogenetic relationships clearly point to the mosaic origin of its genome. Finally, our analysis of the evolution of a small ORF preserved within the 5' leader region of these elements indicates different evolutionary rates, presumably as a result of distinct selective constraints.|
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|Language of Publication||English|
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|Abbreviation||J. Mol. Evol.|
|Title||Journal of Molecular Evolution|
|Data from Reference|
|Natural transposons (5)|