Subject: FlyBase query: EDRC2001: I14, I15 Dear Dr. Dunkov, I am curating your abstracts for the upcoming European Drosophila conference in Edinburgh, for FlyBase. I have questions about 2 abstracts: 1. I14 'Diversity and expression of Drosophila melanogaster transferrins.' You describe 3 transferrin genes in this abstract: Tsf1, Tsf2 and Tsf3. Does Tsf1 correspond to the gene currently called 'Transferrin' in FlyBase (this gene is also known as CG6186) ? Do you know which of the Genome Project CG annotations Tsf2 and Tsf3 correspond to? If Tsf2 and Tsf3 do not correspond to a CG then perhaps you could tell me their map location, as this is valuable information for the genome annotation project. 2. I15 'Probing insect heme catabolism: characterization of Drosophila melanogaster heme oxygenase and biliverdin reductase.' This abstract describes 2 genes that are new to FlyBase: HO (heme oxygenase) and BVR (biliverdin IX-beta reductase). Again could you tell me which CG gene these 2 genes correspond to, or their map location. Any information you give me will be curated as a personal communication from you to FlyBase, Thank you for your help, with best wishes, Gillian \-------------------------------------------------------------- Gillian Millburn. FlyBase (Cambridge), \-------------------------------------------------------------- Subject: Re: FlyBase query: EDRC2001: I14, I15 Dear Gillian, Here are the answers to your questions: >Does Tsf1 correspond to the gene currently called 'Transferrin' in >FlyBase (this gene is also known as CG6186) ? Yes, it does. We chose 'Tsf' for a gene symbol, since 'Tf' and 'Trf' are already taken. > >Do you know which of the Genome Project CG annotations Tsf2 and Tsf3 >correspond to? Tsf2 = CG10620 Tsf3 = CG3666 >This abstract describes 2 genes that are new to FlyBase: HO (heme >oxygenase) and BVR (biliverdin IX-beta reductase). HO = CG14716 BVR = CG9471 there is also a biliverdin IX alpha reductase gene = CG3597 (the gene product is not yet described in the literature, but it probably would be named 'BVRA').. I hope this answers your questions.. Best wishes, Boris Dunkov Department of Biochemistry and Molecular Biophysics University of Arizona BSW \# 351 Tucson, AZ 85719
