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Citation
Aquadro, C.F., Bauer DuMont, V., Reed, F.A. (2001). Genome-wide variation in the human and fruitfly: a comparison.  Curr. Opin. Genet. Dev. 11(6): 627--634.
FlyBase ID
FBrf0139619
Publication Type
Review
Abstract
Average levels of nucleotide diversity are ten-fold lower in humans than in the fruitfly, Drosophila melanogaster. Despite this difference, apparently as a result of a lower population size, patterns of genomic diversity are strikingly similar in being correlated with local rates of recombination, and influenced by similar interactions between positive natural selection and recombination. Both species also show lower levels of variation on average in non-African compared to African populations, reflecting a similar evolutionary history and perhaps both natural selection and founder effects in new environments.
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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Opin. Genet. Dev.
    Title
    Current Opinion in Genetics and Development
    Publication Year
    1991-
    ISBN/ISSN
    0959-437X
    Data From Reference
    Genes (13)