Open Close
Daibo, S., Kimura, M.T., Goto, S.G. (2001). Upregulation of genes belonging to the drosomycin family in diapausing adults of Drosophila triauraria.  Gene 278(1-2): 177--184.
FlyBase ID
Publication Type
Research paper

Diapause-associated gene expression was studied in Drosophila triauraria using subtractive hybridization. Two genes that were shown to be upregulated in diapausing flies by Northern hybridization have similarity to genes encoding antifungal peptides of Drosophila melanogaster, members of the drosomycin family (drosomycin, CG10812, CG10813, CG10815 and CG11520). In addition, a signal peptide and Knot 1 domain are shared with them. The genes cloned from D. triauraria are tentatively named drosomycin-like. However, the similarities between drosomycin-like in D. triauraria and the members of the drosomycin family in D. melanogaster are quite lower than those between other homologous genes in these species. In addition, neighbor-joining analysis revealed that drosomycin-like in D. triauraria is not closely related to known members of the family in D. melanogaster. Thus, it is most plausible that drosomycin-like is not a D. triauraria counterpart of known members of the family, but a novel member belonging to the family. The drosomycin-like gene is expected to have a few copies, because at least two sequences having unique 3'-ends were obtained in RACE, and multiple bands were observed in Southern hybridization. However, these sequences from RACE had the same ORF. Probes for genes encoding additional antimicrobial peptides were used to evaluate expression during diapause. Like drosomycin-like, drosomycin was upregulated during diapause, but defensin and drosocin were not.

PubMed ID
PubMed Central ID
Associated Information
Associated Files
Other Information
Secondary IDs
    Language of Publication
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Publication Year
    Data From Reference
    Genes (8)