A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Reference Report

Reference
Citation Rosin, D., Shilo, B.Z. (2002). Branch-specific migration cues in the Drosophila tracheal system.  BioEssays 24(2): 110--113. (Export to RIS)
FlyBase ID FBrf0144739
Publication Type Review
PubMed ID 11835274
PubMed Abstract The Drosophila tracheal system forms by highly stereotyped migration of the tracheal cells, generating an elaborate network of interconnected tubes supplying oxygen to all tissues. A major guiding system in the migration process of all branches is the dynamic and localized expression of Branchless (Bnl), an FGF-like molecule. Bnl triggers the activation of the FGF receptor Breathless (Btl) locally in all tracheal cells. Is this the only guiding cue, or do additional local signals provide distinct inputs to each branch? Several recent papers identify such local signals, relying on contacts with specific cell types and with the matrix encountered by the migrating tracheal branches. In particular, the paper by Boube et al(1) demonstrates a role for PS integrins in promoting migration of a specific tracheal branch.
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Language of Publication English
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Publication Type Journal
Abbreviation BioEssays
Title BioEssays
Publication Year 1984-
ISBN/ISSN 0265-9247
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