Reference Report

Reference
Citation	Kumar, M., Joseph, M., Chandrashekaran, S. (2001). Effects of mutations at the stambh A locus of Drosophila melanogaster. J. Genet. 80(2): 83--95. (Export to RIS)
FlyBase ID	FBrf0144960
Publication Type	Research paper
PubMed ID	11910128
PubMed Abstract	We report novel findings on the cytogenetic location, functional complexity and maternal and germline roles of the stambh A locus of Drosophila melanogaster. stmA is localized to polytene bands 44D1.2 on 2R. stmA mutations are of two types: temperature-sensitive (ts) adult and larval paralytic or unconditional embryonic or larval lethal. Twelve alleles reported in this study fall into two intragenic complementing groups suggesting that stmA is a complex locus with more than one functional domain. Some unconditional embryonic lethal alleles show a 'neurogenic' phenotype of cuticle loss accompanied by neural hypertrophy. It is shown that embryos of ts paralytic alleles also show mild neural hypertrophy at permissive temperatures while short exposure to heat induces severe cuticle loss in these embryos. stmA exerts a maternal influence over heat-induced cuticle loss. Unconditional embryonic lethal alleles of stmA are also germline lethal.
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Language of Publication	English
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Publication Type	Journal
Abbreviation	J. Genet.
Title	Journal of Genetics
Publication Year	1910-
ISBN/ISSN	0022-1333
Data from Reference
Aberrations (6)
	Df(2R)44CE Df(2R)cn9 Df(2R)cn87e Df(2R)H3C1 Df(2R)H3E1 Df(2R)stmA-12
Alleles (20)
	stmA^1-2 stmA^1-4 stmA¹ stmA^2-2 stmA² stmA⁷ stmA¹² stmA^18-2 stmA^27-1 stmA^KP1 stmA^KP2 stmA^KP3 stmA^KP4 stmA^KP5 stmA^KP6 stmA^p1 stmA^p2 stmA^p3 stmA^p4 stmA^p5
Genes (1)
	stmA