A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Reference Report

Reference
Citation Alvarez-Venegas, R., Avramova, Z. (2002). SET-domain proteins of the Su(var)3-9, E(z) and trithorax families.  Gene 285(1-2): 25--37. (Export to RIS)
FlyBase ID FBrf0149567
Publication Type Review
PubMed ID 12039029
PubMed Abstract SET-domain (SET: Su(var)3-9, E(z) and Trithorax)-containing proteins were collected through sequence searches of the available databases. After removing redundancies, the proteins belonging to three families, SU(VAR)3-9, E(Z) and Trithorax, were selected. Analysis of the relationship between the different members is based on pairwise alignment, compilation, and comparison of their SET-domains. The level of homology of the SET-domains defined the distribution of the proteins into families and into clades within the families. The architecture of the entire protein supported the distribution pattern built upon SET-domain similarity. Parallel cladistic and protein-architecture analyses outlined two plausible criteria for predicting function.
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Language of Publication English
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Publication Type Journal
Abbreviation Gene
Title Gene
Publication Year 1976-
ISBN/ISSN 0378-1119
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