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Carpenter, A.T.C. (2002.4.2). In(3L)A54 and cu2
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FBrf0149628
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Personal communication to FlyBase
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From kcook@XXXX Sat May 25  15:47:00  2002
To: flybase-updates@XXXX
Subject: In(3L)A54 and cu2
The following information accompanied a stock donated to the Bloomington
Stock Center by Adelaide Carpenter, Cambridge University (4/02).
In(3L)A54 was induced by X-ray treatment of a st1 pp red1 e4
chromosome. Its breakpoints are 65A7-15;69B3-C11;72E3-F4 and its new
cytological order is
3Lt \- 65A7 | insertion of 6 bands of unknown origin | 69B3 \- 65A15 | 72E3 \-
69C11 | 72F4 \-3Rt.
The inversion complex is associated with homozygous lethality and a
dominant gapped wing vein phenotype involving L4.
In combination with Df(3L)E44 or Df(3L)F10, recessive phenotypes are
seen. These include missing mid-thorax, reduced eyes and aristae, and
held-up wings. These recessive phenotypes may reflect effects of the 69BC
inversion breakpoint on gv and eyg. Viability is low with many uneclosed
pupae. When dissected, these pupae are headless (except for the presence
of palps) or have very reduced heads. They also show the thoracic defects
seen in the viable escapers.
The X-ray treatment also induced a new allele of cu, called cu2,
identified by its curled wing phenotype in combination with cu1. There
is no cytologically visible aberration in region 86 where the cu locus
maps. cu2 can be separated from the inversion complex by meiotic
recombination.
__________________________________________________________
Kevin Cook, Ph.D. Bloomington Drosophila Stock Center
Department of Biology http://flystocks.bio.indiana.edu
Jordan Hall 142
Indiana University 812-855-5782
1001 E. Third St. 812-855-2577 (fax)
Bloomington, IN 47405-3700 kcook@XXXX
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    English
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    Aberrations (3)
    Alleles (6)
    Genes (1)