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Citation
Boube, M., Joulia, L., Cribbs, D.L., Bourbon, H.M. (2002). Evidence for a mediator of RNA polymerase II transcriptional regulation conserved from yeast to man.  Cell 110(2): 143--151.
FlyBase ID
FBrf0151648
Publication Type
Review
Abstract

Mediator complexes (MED) link transcriptional regulators to RNA polymerase II. Here, we summarize the latest advances on the functional organization of yeast Mediator. We argue for the existence of a "universal" Mediator structurally conserved from yeast to man, based on an extensive analysis of sequence databases. Finally, we examine the implications of these observations for the physiological roles of metazoan MED subunits.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cell
    Title
    Cell
    Publication Year
    1974-
    ISBN/ISSN
    0092-8674
    Data From Reference
    Genes (14)