|Citation||Maggert, K.A., Golic, K.G. (2002). The Y chromosome of Drosophila melanogaster exhibits chromosome-wide imprinting. Genetics 162(3): 1245--1258. (Export to RIS)|
|Publication Type||Research paper|
|PubMed Abstract||Genomic imprinting is well known as a regulatory property of a few specific chromosomal regions and leads to differential behavior of maternally and paternally inherited alleles. We surveyed the activity of two reporter genes in 23 independent P-element insertions on the heterochromatic Y chromosome of Drosophila melanogaster and found that all but one location showed differential expression of one or both genes according to the parental source of the chromosome. In contrast, genes inserted in autosomal heterochromatin generally did not show imprint-regulated expression. The imprints were established on Y-linked transgenes inserted into many different sequences and locations. We conclude that genomic imprinting affecting gene expression is a general property of the Drosophila Y chromosome and distinguishes the Y from the autosomal complement.|
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|Language of Publication||English|
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|Natural transposons (6)|