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Citation
Marygold, S.J., Leevers, S.J. (2002). Growth signaling: tSC takes its place.  Curr. Biol. 12(22): R785--R787.
FlyBase ID
FBrf0155624
Publication Type
Review
Abstract

The protein products of the tumor suppressor genes tuberous sclerosis complex 1 and 2 form a protein complex, TSC1-TSC2, that inhibits growth. Several new studies suggest that TSC1-TSC2 does this by inhibiting TOR and S6 kinase, and that PI 3-kinase-Akt signaling relieves this inhibition.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Curr. Biol.
    Title
    Current Biology
    Publication Year
    1991-
    ISBN/ISSN
    0960-9822
    Data From Reference
    Genes (10)