Reference Report

Reference
Citation	Hosono, C., Takaira, K., Matsuda, R., Saigo, K. (2003). Functional subdivision of trunk visceral mesoderm parasegments in Drosophila is required for gut and trachea development. Development 130(3): 439--449. (Export to RIS)
FlyBase ID	FBrf0155713
Publication Type	Research paper
PubMed ID	12490551
PubMed Abstract	In Drosophila, trunk visceral mesoderm, a derivative of dorsal mesoderm, gives rise to circular visceral muscles. It has been demonstrated that the trunk visceral mesoderm parasegment is subdivided into at least two domains by connectin expression, which is regulated by Hedgehog and Wingless emanating from the ectoderm. We now extend these findings by examining a greater number of visceral mesodermal genes, including hedgehog and branchless. Each visceral mesodermal parasegment appears to be divided into five or six regions, based on differences in expression patterns of these genes. Ectodermal Hedgehog and Wingless differentially regulate the expression of these metameric targets in trunk visceral mesoderm. hedgehog expression in trunk visceral mesoderm is responsible for maintaining its own expression and con expression. hedgehog expressed in visceral mesoderm parasegment 3 may also be required for normal decapentaplegic expression in this region and normal gastric caecum development. branchless expressed in each trunk visceral mesodermal parasegment serves as a guide for the initial budding of tracheal visceral branches. The metameric pattern of trunk visceral mesoderm, organized in response to ectodermal instructive signals, is thus maintained at a later time via autoregulation, is required for midgut morphogenesis and exerts feedback effect on trachea, ectodermal derivatives.
DOI
Related Publication(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
Language of Publication	English
Additional Languages of Abstract
Also Published As
Parent Publication
Publication Type	Journal
Abbreviation	Development
Title	Development
Publication Year	1987-
ISBN/ISSN	0950-1991
Data from Reference
Alleles (16)
	bnl^Scer\UAS.cSa ci::en^{Zn:RD.Scer\UAS.T:Hsap\MYC} Ecol\lacZ^bap.4.5 Ecol\lacZ^ftz.PC Ecol\lacZ^hh.VM hh⁴ hh⁸ hh^Scer\UAS.cKa pan^ΔN.Scer\UAS Scer\GAL4^48Y Scer\GAL4^bap.3 Scer\GAL4^how-24B Scer\GAL4^twi.PGa wg^l-12 wg^l-17 wg^{Scer\UAS.cHa.T:Ivir\HA1}
Constructs (10)
	P{bap-GAL4.3} P{bap-lacZ.4.5} P{ftz/lacC} P{hh-lacZ.VM} P{twi-GAL4.Ga} P{UAS-ciZn/EnRD} P{UAS-hh.K} P{UAS-pan.dTCFΔN} P{UAS-wg.H.T:HA1} P{UAS-wg.H}
Genes (17)
	bap bnl ci::en Con dpp Ecol\lacZ Fas3 hh pan ptc Scer\GAL4 T:Hsap\MYC T:Ivir\HA1 tin vn wg Wnt4
Insertions (3)
	P{bap-lacZ.4.5}23 P{GawB}48Y P{GawB}how^24B