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Citation
Simpson, P. (2002). Evolution of development in closely related species of flies and worms.  Nat. Rev. Genet. 3(12): 907--917.
FlyBase ID
FBrf0155986
Publication Type
Review
Abstract
One of the main challenges in evolutionary biology is to identify the molecular changes that underlie phenotypic differences that are of evolutionary significance. Comparative studies of early development have shown that changes in the spatio-temporal use of regulatory genes, as well as changes in the specificity of regulatory proteins, are correlated with important differences in morphology between phylogenetically distant species. However, it is not known how such changes take place in natural populations, and whether they result from a single, or many small, additive events. Extending this approach to the study of development of closely related species promises to enrich this debate.
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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Nat. Rev. Genet.
    Title
    Nature Reviews. Genetics
    Publication Year
    2000-
    ISBN/ISSN
    1471-0056 1471-0064
    Data From Reference