Reference Report

Reference
Citation	Schloetterer, C. (2003). Hitchhiking mapping: functional genomics from the population genetics perspective. Trends Genet. 19(1): 32--38. (Export to RIS)
FlyBase ID	FBrf0156098
Publication Type	Review
PubMed ID	12493246
PubMed Abstract	Several statistical tests based on population genetic theory are used to identify genes that have recently acquired a beneficial mutation. Here, I describe the extension of these tests to a multilocus approach for a genome-wide survey for genes that have been under recent positive selection. As this strategy could potentially identify genes with weak phenotypic effects, it will be very useful in population genetic approaches aimed at understanding adaptation processes in natural populations. Furthermore, this 'hitchhiking mapping' could also help in the functional characterization of genomes.
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Language of Publication	English
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Publication Type	Journal
Abbreviation	Trends Genet.
Title	Trends in Genetics
Publication Year	1985-
ISBN/ISSN	0168-9525
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	Sdic Su(H) Vha68-1