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Citation
Billuart, P., Chelly, J. (2003). From fragile X mental retardation protein to Rac1 GTPase: new insights from Fly CYFIP.  Neuron 38(6): 843--845.
FlyBase ID
FBrf0160414
Publication Type
Note
Abstract

Mutations in either the Rho GTPase pathway or in the fragile X mental retardation (FMR1) gene produce neuronal connectivity defects. In this issue of Neuron, Schenck et al. use biochemical and genetic approaches in Drosophila to examine the interactions between dFMR1 and dRac1 and provide evidence that the cytoplasmic FMRP interacting protein (CYFIP) links Rac-dependent cytoskeleton remodeling and dFMR1-dependent control of translation in a unique pathway to modulate neuronal morphogenesis.

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PubMed Central ID
Related Publication(s)
Research paper

CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein.
Schenck et al., 2003, Neuron 38(6): 887--898 [FBrf0160918]

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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Neuron
    Title
    Neuron
    Publication Year
    1988-
    ISBN/ISSN
    0896-6273
    Data From Reference
    Genes (6)