A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Reference Report

Reference
Citation Gruntenko, N.E., Chentsova, N.A., Andreenkova, E.V., Bownes, M., Segal, D., Adonyeva, N.V., Rauschenbach, I.Y. (2003). Stress response in a juvenile hormone-deficient Drosophila melanogaster mutant apterous56f.  Insect Mol. Biol. 12(4): 353--363. (Export to RIS)
FlyBase ID FBrf0160575
Publication Type Research paper
PubMed ID 12864915
PubMed Abstract The apterous56f (ap56f) mutation leads to increases in juvenile hormone (JH) degradation levels and JH-esterase makes a greater contribution to the increase than JH-epoxide hydrolase. Dopamine levels in ap56f females, but not males, are higher than in wild-type. JH treatment of ap56f and wild-type females decreases their dopamine levels. ap56f females, but not males, produce less progeny. Survival under heat stress is dramatically decreased in ap56f females, but not males. ap56f flies show a stress reaction, as judged by changes in tyrosine decarboxylase and JH-hydrolysing activities, dopamine levels and fertility, but its intensity in the mutant females, but not males, differs significantly from wild-type. Thus, the ap56f mutation causes dramatic changes in female, but not male, metabolism and fitness.
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Language of Publication English
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Publication Type Compendium
Abbreviation Insect Mol. Biol.
Title Insect Molecular Biology
Publication Year 1992-
ISBN/ISSN 0307-6975
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