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Reference Report
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| Citation | Cook, T. (2003). Cell diversity in the retina: more than meets the eye. BioEssays 25(10): 921--925. (Export to RIS) | ||
| FlyBase ID | FBrf0161963 | ||
| Publication Type | Review | ||
| PubMed ID | 14505358 | ||
| PubMed Abstract | Over 10 years ago, Pax-6 was shown to play an evolutionarily conserved role in controlling eye formation from Drosophila to humans.1 Since then, the identification of an entire cascade of conserved eye determination genes has brought a new understanding to the developmental relationship between the insect compound eye and the vertebrate camera eye.2 Additional studies are now beginning to suggest that even late aspects of eye development, including cell type specification, also share common molecular machinery. In this commentary, I will discuss some of these findings, with a particular focus on the recent study by Dyer et al.3 describing a novel role for the Prox1 transcription factor in specifying horizontal cells in the mouse retina. As Prospero, the Drosophila homolog of Prox1, also participates in retinal cell specification, these data provide a forum for asking new questions concerning pathways that may regulate retinogenesis across evolution. | ||
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| FB2013_03 | |||
| FB2013_02 | |||
| All updates | Click here to see a list of all updates to this record from FB2010_08 and on. | ||
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| Language of Publication | English | ||
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Parent Publication
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| Publication Type | Journal | ||
| Abbreviation | BioEssays | ||
| Title | BioEssays | ||
| Publication Year | 1984- | ||
| ISBN/ISSN | 0265-9247 | ||
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Data from Reference
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| Genes (13)
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