Reference Report

Reference
Citation	Lukacsovich, T., Yuge, K., Awano, W., Asztalos, Z., Kondo, S., Juni, N., Yamamoto, D. (2003). The ken and barbie gene encoding a putative transcription factor with a BTB domain and three zinc finger motifs functions in terminalia development of Drosophila. Arch. Insect Biochem. Physiol. 54(2): 77--94. (Export to RIS)
FlyBase ID	FBrf0167302
Publication Type	Research paper
PubMed ID	14518006
PubMed Abstract	Mutations in the ken and barbie locus are accompanied by the malformation of terminalia in adult Drosophila. Male and female genitalia often remain inside the body, and the same portions of genitalia and analia are missing in a fraction of homozygous flies. Rotated and/or duplicated terminalia are also observed. Terminalia phenotypes are enhanced by mutations in the gap gene tailless, the homeobox gene caudal, and the decapentaplegic gene that encodes a TGFbeta-like morphogen. The ken and barbie gene encodes a protein with three CCHH-type zinc finger motifs that are conserved in several transcription factors such as Krüppel and BCL-6. All defects in ken and barbie mutants are fully rescued by the expression of a wild-type genomic construct, which establishes the causality between phenotypes and the gene.
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Language of Publication	English
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Parent Publication
Publication Type	Journal
Abbreviation	Arch. Insect Biochem. Physiol.
Title	Archives of Insect Biochemistry and Physiology
Publication Year	1984-
ISBN/ISSN	0739-4462
Data from Reference
Alleles (16)
	cad^md509 dpp^d5 Ecol\lacZ^dpp.BS3.0 Ecol\lacZ^ken-1 ken¹ ken⁰⁰⁶²⁸ ken⁰²⁹⁷⁰ ken⁰³⁹⁰⁷ ken^+t9 ken^hs.PL ken^k11035 ken^ok ken^ok-Rev1 ken^Scer\UAS.cLa tll^l49 w^+mC
Constructs (4)
	P{BS3.0} P{hs-ken.L} P{ken^+t9} P{UAS-ken.L}
Genes (10)
	cad CG4585 CG4882 dpp Ecol\lacZ ken Thiolase tll TM4SF w
Insertions (6)
	P{GawB}cad^md509 P{lacW}ken^k11035 P{PZ}ken¹ P{PZ}ken⁰⁰⁶²⁸ P{PZ}ken⁰²⁹⁷⁰ P{PZ}ken⁰³⁹⁰⁷
Natural transposons (1)
	297