Reference Report

Reference
Citation	Shi, W., Stampas, A., Zapata, C., Baker, N.E. (2003). The pineapple eye gene is required for survival of Drosophila imaginal disc cells. Genetics 165(4): 1869--1879. (Export to RIS)
FlyBase ID	FBrf0167647
Publication Type	Research paper
External Crossreferences
PubMed ID	14704172
PubMed Abstract	Each ommatidium of the Drosophila eye is constructed by precisely 19 specified precursor cells, generated in part during a second mitotic wave of cell divisions that overlaps early stages of ommatidial cell specification. Homozygotes for the pineapple eye mutation lack sufficient precursor cells due to apoptosis during the period of fate specification. In addition development is delayed by apoptosis during earlier imaginal disc growth. Null alleles are recessive lethal and allelic to l(2)31Ek; heteroallelic combinations can show developmental delay, abnormal eye development, and reduced fertility. Mosaic clones autonomously show extensive cell death. The pineapple eye gene was identified and predicted to encode a novel 582-amino-acid protein. The protein contains a novel, cysteine-rich domain of 270 amino acids also found in predicted proteins of unknown function from other animals.
BIOSIS ID	2004.94984
Zoological Record ID
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Associated Information
Comments
Text of Personal Communication
Associated Files
Other Information
Secondary IDs
Language of Publication	English
Additional Languages of Abstract
ISBN
Parent Publication
Publication Type	Journal
Abbreviation	Genetics
Title	Genetics
Editors
Publication Year	1916-
ISBN/ISSN	0016-6731
Data from Reference
Aberrations (8)
	Df(2L)J2 Df(2L)J16 Df(2L)J17 Df(2L)J27 Df(2L)J39 Df(2L)J77 Df(2L)J106 In(2L)pie^G2-4
Alleles (13)
	BacA\p35^GMR.PH Fatp^k10307 Hsap\CDKN1A^GMR.PH pie⁵⁴ pie^E1-2 pie^E1-16 pie^EB3 pie^G2-4 pie^H113 pie^QM47 W⁰⁵⁰¹⁴ W^rvX1 W^unspecified
Constructs (2)
	P{GMRp21^B} P{GMRP35}
Genes (9)
	BacA\p35 ct CycB elav Fatp Hsap\CDKN1A l(2)53Da pie W
Insertions (2)
	P{lacW}k08229 P{PZ}W⁰⁵⁰¹⁴