A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Reference Report

Reference
Citation Salcedo, E., Zheng, L., Phistry, M., Bagg, E.E., Britt, S.G. (2003). Molecular basis for ultraviolet vision in invertebrates.  J. Neurosci. 23(34): 10873--10878. (Export to RIS)
FlyBase ID FBrf0167803
Publication Type Research paper
PubMed ID 14645481
PubMed Abstract Invertebrates are sensitive to a broad spectrum of light that ranges from UV to red. Color sensitivity in the UV plays an important role in foraging, navigation, and mate selection in both flying and terrestrial invertebrate animals. Here, we show that a single amino acid polymorphism is responsible for invertebrate UV vision. This residue (UV: lysine vs blue:asparagine or glutamate) corresponds to amino acid position glycine 90 (G90) in bovine rhodopsin, a site affected in autosomal dominant human congenital night blindness. Introduction of the positively charged lysine in invertebrates is likely to deprotonate the Schiff base chromophore and produce an UV visual pigment. This same position is responsible for regulating UV versus blue sensitivity in several bird species, suggesting that UV vision has arisen independently in invertebrate and vertebrate lineages by a similar molecular mechanism.
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Language of Publication English
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Publication Type Journal
Abbreviation J. Neurosci.
Title Journal of Neuroscience
Publication Year 1981-
ISBN/ISSN 0270-6474 1529-2401
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