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Reference Report
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| Citation | Wilson, R.I., Turner, G.C., Laurent, G. (2004). Transformation of olfactory representations in the Drosophila antennal lobe. Science 303(5656): 366--370. (Export to RIS) | ||
| FlyBase ID | FBrf0168036 | ||
| Publication Type | Research paper | ||
| PubMed ID | 14684826 | ||
| PubMed Abstract | Molecular genetics has revealed a precise stereotypy in the projection of primary olfactory sensory neurons onto secondary neurons. A major challenge is to understand how this mapping translates into odor responses in these second-order neurons. We investigated this question in Drosophila using whole-cell recordings in vivo. We observe that monomolecular odors generally elicit responses in large ensembles of antennal lobe neurons. Comparison of odor-evoked activity from afferents and postsynaptic neurons in the same glomerulus revealed that second-order neurons display broader tuning and more complex responses than their primary afferents. This indicates a major transformation of odor representations, implicating lateral interactions within the antennal lobe. | ||
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| FB2013_03 | |||
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| All updates | Click here to see a list of all updates to this record from FB2010_08 and on. | ||
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| Language of Publication | English | ||
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| Publication Type | Journal | ||
| Abbreviation | Science | ||
| Title | Science | ||
| Publication Year | 1895- | ||
| ISBN/ISSN | 0036-8075 | ||
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Data from Reference
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| Alleles (4)
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| Constructs (2)
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| Genes (4)
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| Insertions (2)
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| Transcripts (1)
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