For annotations documented via this citation, GO terms were assigned to FlyBase genes through InterPro protein domain assignments. Where an InterPro entry hits a set of functionally similar proteins, GO terms describing the conserved function or location are associated with the InterPro entry manually by the InterPro team at the EBI. The InterPro2GO file is available at http://www.geneontology.org/external2go/interpro2go.
The mapping file is used to assign annotations to UniProtKB proteins at each EBI GOA release. GO annotations using this technique receive the evidence code Inferred from Electronic Annotation (IEA). FlyBase imports and updates these annotations every release.