Tools
Tools Overview & Help
Query by symbols/IDs
Batch Download
Sequence Downloader
ID Validator
Feature Mapper
Search/Browse Portals
QuickSearch
Vocabularies
QueryBuilder
CytoSearch
Interactions Browser
ImageBrowse
Genomics Tools
BLAST
JBrowse
CytoSearch
Feature Mapper
Chromosome Maps
Coordinates Converter
Sequence Downloader
modENCODE RNA-Seq
Overview
RNA-Seq Similarity
RNA-Seq Profile
RNA-Seq By Region
JBrowse
Submit Data
Fast-Track Your Paper
Submit Personal Communication
Feedback on Gene Snapshots
Downloads
Overview
Current Release
Archived Data
Map Conversion
FTP Site:
Releases (FTP)
Genomes (FTP)
Links
External Resources
Model Organisms (MODs)
Alliance of Genome Resources
BeeBase
DictyBase
EcoCyc
Gramene
MGI
PomBase
Pseudobase
RGD
SGD
TAIR
VectorBase
WormBase
Xenbase
ZFIN
Stock Collections
Bloomington Drosophila Stock Center (BDSC)
FlyORF
Korea Drosophila Resource Center (KDRC)
Kyoto Stock Center
NIG-FLY
Tsinghua Fly Center (THFC)
Vienna Drosophila Resource Center (VDRC)
BDGP
DGRC
DRSC/TRiP
DIS by issue
FlyBook
FlyExpress
Interactive Fly
Virtual Fly Brain
FlyCyc
Community
Fast-Track Your Paper
FlyBase Community
Advisory Group
Fly Lab List
Recent Papers With
Technical Advances
Gene Snapshots
FlyBase Forum
Newsletter
FlySlack Community
Mastodon
Bluesky
X (formerly Twitter)
Fly Board
NIH Funding
Species
Phylogeny
Sequenced Species
Synteny Table
Color Illustrations
About
Release Notes
New In This Release
Release Schedule
FlyBase Positions
Citing FlyBase
FlyBase Licensing
FlyBase Consortium
FlyBase Publications
FlyBase Presentations
Grants Supporting FlyBase
Help
Contact FlyBase
FlyBase Wiki:
Help Index
Tool help
Report help
FlyBase FAQ
Info for Authors
Author guidelines
Citing FlyBase
Fast-Track Your Paper Help
Gene Snapshots
Personal communications
Linking to/from FlyBase
Nomenclature
Curation documentation
Controlled Vocabularies in FlyBase
Gene Model Annotation
Gene Ontology (GO) Annotation
Nontraditional alleles
Vectors & Constructs
New to Flies?
Video Tutorials
Programmatic Access
to FlyBase: APIs, etc.
Outreach Funding Opportunity
FlyBase IP blocks
66
th
ADRC
New Metabolic Pathway reports
Bulk data best practices
Previous
Next
FB2025_01
,
released February 20, 2025
Tools
Tools Overview & Help
Query by symbols/IDs
Batch Download
Sequence Downloader
ID Validator
Feature Mapper
Search/Browse Portals
QuickSearch
Vocabularies
QueryBuilder
CytoSearch
Interactions Browser
ImageBrowse
Genomics Tools
BLAST
JBrowse
CytoSearch
Feature Mapper
Chromosome Maps
Coordinates Converter
Sequence Downloader
modENCODE RNA-Seq
Overview
RNA-Seq Similarity
RNA-Seq Profile
RNA-Seq By Region
JBrowse
Submit Data
Fast-Track Your Paper
Submit Personal Communication
Feedback on Gene Snapshots
Downloads
Overview
Current Release
Archived Data
Map Conversion
FTP Site:
Releases (FTP)
Genomes (FTP)
Links
External Resources
Model Organisms (MODs)
Alliance of Genome Resources
BeeBase
DictyBase
EcoCyc
Gramene
MGI
PomBase
Pseudobase
RGD
SGD
TAIR
VectorBase
WormBase
Xenbase
ZFIN
Stock Collections
Bloomington Drosophila Stock Center (BDSC)
FlyORF
Korea Drosophila Resource Center (KDRC)
Kyoto Stock Center
NIG-FLY
Tsinghua Fly Center (THFC)
Vienna Drosophila Resource Center (VDRC)
BDGP
DGRC
DRSC/TRiP
DIS by issue
FlyBook
FlyExpress
Interactive Fly
Virtual Fly Brain
FlyCyc
Community
Fast-Track Your Paper
FlyBase Community
Advisory Group
Fly Lab List
Recent Papers With
Technical Advances
Gene Snapshots
FlyBase Forum
Newsletter
FlySlack Community
Mastodon
Bluesky
X (formerly Twitter)
Fly Board
NIH Funding
Species
Phylogeny
Sequenced Species
Synteny Table
Color Illustrations
About
Release Notes
New In This Release
Release Schedule
FlyBase Positions
Citing FlyBase
FlyBase Licensing
FlyBase Consortium
FlyBase Publications
FlyBase Presentations
Grants Supporting FlyBase
Help
Contact FlyBase
FlyBase Wiki:
Help Index
Tool help
Report help
FlyBase FAQ
Info for Authors
Author guidelines
Citing FlyBase
Fast-Track Your Paper Help
Gene Snapshots
Personal communications
Linking to/from FlyBase
Nomenclature
Curation documentation
Controlled Vocabularies in FlyBase
Gene Model Annotation
Gene Ontology (GO) Annotation
Nontraditional alleles
Vectors & Constructs
New to Flies?
Video Tutorials
Programmatic Access
to FlyBase: APIs, etc.
Outreach Funding Opportunity
FlyBase IP blocks
66
th
ADRC
New Metabolic Pathway reports
Bulk data best practices
Previous
Next
FB2025_01
,
released February 20, 2025
Reference Report
J2G
Search
Go
Open
Close
Reference
Citation
Torroja, C., Gorfinkiel, N., Guerrero, I. (2004). Patched controls the Hedgehog gradient by endocytosis in a dynamin-dependent manner, but this internalization does not play a major role in signal transduction.
Development
131(10)
: 2395--2408.
FlyBase ID
FBrf0174584
Publication Type
Research paper
Abstract
PubMed ID
15102702
PubMed Central ID
DOI
10.1242/dev.01102
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
Language of Publication
English
Additional Languages of Abstract
Parent Publication
Publication Type
Journal
Abbreviation
Development
Title
Development
Publication Year
1987-
ISBN/ISSN
0950-1991
Data From Reference
Alleles (25)
Export to HitList
disp
S037707
dor
8
Ecol\lacZ
dpp-10638
Ecol\lacZ
dpp.BS3.0
Ecol\lacZ
ptc-H84
hh
ts2
hh
UAS.EGFP
ptc
14.UAS.EGFP
ptc
14
ptc
16
ptc
S2.UAS.EGFP
ptc
S2.UAS
ptc
S2
ptc
UAS.EGFP
Rab7
UAS.GFP
Scer\GAL4
AB1
Scer\GAL4
Act5C.PP
Scer\GAL4
C-765
Scer\GAL4
en-e16E
Scer\GAL4
FRT.Rnor\Cd2.Act5C
Scer\GAL4
FRT.Ubx
Scer\GAL4
hh-Gal4
Scer\GAL4
ptc-559.1
Scer\GAL4
Ubx.PdC
shi
1
Genes (13)
Export to HitList
ci
disp
dor
dpp
Ecol\lacZ
en
hh
kn
ptc
Rab7
Scer\GAL4
shi
smo
Insertions (7)
Export to HitList
P{A92}ptc
H84
P{en2.4-GAL4}e16E
P{GAL4}hh
Gal4
P{GawB}AB1
P{GawB}C-765
P{GawB}ptc
559.1
P{PZ}dpp
10638
Experimental Tools (2)
Export to HitList
EGFP
UAS
Transgenic Constructs (11)
Export to HitList
P{BS3.0}
P{GAL4-Act5C(FRT.CD2).P}
P{GAL4-Act5C(-FRT).P}
P{GAL4-lacZ-Ubx(FRT.f
+
).dC}
P{GAL4-lacZ-Ubx(-FRT).dC}
P{UAS-hh.GFP}
P{UAS-ptc.GFP}
P{UAS-ptc.S2}
P{UAS-ptc
14
GFP}
P{UAS-ptc
S2
GFP}
P{UAS-Rab7.GFP}
Report Sections
Open
Close
Reference
Associated Information
Other Information
Parent Publication
Data From Reference