|Citation||Herr, D.R., Harris, G.L. (2004). Close head-to-head juxtaposition of genes favors their coordinate regulation in Drosophila melanogaster. FEBS Lett. 572(1-3): 147--153. (Export to RIS)|
|Publication Type||Research paper|
|PubMed Abstract||This report identifies a large number of gene-pairs in Drosophila melanogaster that share a common upstream region. 877 gene-pairs (approximately 12% of the genome) are separated by less than 350 bp in a head-to-head orientation. This positional relationship is more highly favored in flies than in other organisms. These gene pairs have a higher correlation of expression than similarly spaced genes that have head-to-tail or tail-to-tail orientations. Thus, the positional arrangement of genes appears to play a significant role in coordinating relative expression patterns and may provide clues for identifying the functions of unknown genes.|
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|Language of Publication||English|
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