A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Reference Report

Reference
Citation Herr, D.R., Harris, G.L. (2004). Close head-to-head juxtaposition of genes favors their coordinate regulation in Drosophila melanogaster.  FEBS Lett. 572(1-3): 147--153. (Export to RIS)
FlyBase ID FBrf0179781
Publication Type Research paper
PubMed ID 15304339
PubMed Abstract This report identifies a large number of gene-pairs in Drosophila melanogaster that share a common upstream region. 877 gene-pairs (approximately 12% of the genome) are separated by less than 350 bp in a head-to-head orientation. This positional relationship is more highly favored in flies than in other organisms. These gene pairs have a higher correlation of expression than similarly spaced genes that have head-to-tail or tail-to-tail orientations. Thus, the positional arrangement of genes appears to play a significant role in coordinating relative expression patterns and may provide clues for identifying the functions of unknown genes.
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Language of Publication English
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Publication Type Journal
Abbreviation FEBS Lett.
Title FEBS Letters
Publication Year 1968-
ISBN/ISSN 0014-5793
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