Reference Report

Reference
Citation	Ivanov, A.I., Rovescalli, A.C., Pozzi, P., Yoo, S., Mozer, B., Li, H.P., Yu, S.H., Higashida, H., Guo, V., Spencer, M., Nirenberg, M. (2004). Genes required for Drosophila nervous system development identified by RNA interference. Proc. Natl. Acad. Sci. U.S.A. 101(46): 16216--16221. (Export to RIS)
FlyBase ID	FBrf0180653
Publication Type	Research paper
PubMed ID	15534205
PubMed Abstract	RNA interference was used to screen 3,314 Drosophila double-stranded RNAs, corresponding to approximately 25% of Drosophila genes, for genes that affect the development of the embryonic nervous system. RNA-interference-mediated gene silencing in Drosophila embryos resulted in loss-of-function mutant phenotypes for 43 genes, which is 1.3% of the genes that were screened. We found 18 genes that were not known previously to affect the development of the nervous system. The functions of some of the genes are unknown. Other genes encode protein kinases, transcription factors, and signaling proteins, as well as proteins with other functions.
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Language of Publication	English
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Publication Type	Journal
Abbreviation	Proc. Natl. Acad. Sci. U.S.A.
Title	Proceedings of the National Academy of Sciences of the United States of America
Publication Year	1915-
ISBN/ISSN	0027-8424
Data from Reference
Alleles (38)
	bib^dsRNA.cIa Bx42^dsRNA.cIa CG6015^dsRNA.cIa CG9821^dsRNA.cIa CG30089^dsRNA.cIa CG30497^dsRNA.cIa CkIIβ^dsRNA.cIb CkIα^dsRNA.cIa comm^dsRNA.cIa da^dsRNA.cIa Dl^dsRNA.cIa e(y)3^dsRNA.cIa ed^dsRNA.cIa Egfr^dsRNA.cIa en^dsRNA.cIa fra^dsRNA.cIa gwl^dsRNA.cIa lola^dsRNA.cIa mam^dsRNA.cIa mei-P26^dsRNA.cIa Mhcl^dsRNA.cIa mor^dsRNA.cIa N^dsRNA.cIa plexA^dsRNA.cIa ptc^dsRNA.cIa put^dsRNA.cIa robo^dsRNA.cIa SAK^dsRNA.cIa seq^dsRNA.cIa sli^dsRNA.cIa smo^dsRNA.cIa SoxN^dsRNA.cIa SrpRβ^dsRNA.cIa Su(H)^dsRNA.cIa th^dsRNA.cIa tkv^dsRNA.cIa ttk^dsRNA.cIa twi^dsRNA.cIa
Genes (40)
	bib Bx42 CG6015 CG9821 CG30089 CG30497 CkIIβ CkIα comm da Dl e(y)3 ed Egfr en Fas2 fra futsch gwl lola mam mei-P26 Mhcl mor N plexA ptc put robo SAK seq sli smo SoxN SrpRβ Su(H) th tkv ttk twi