A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Reference Report

Reference
Citation Beinert, N., Werner, M., Dowe, G., Chung, H.R., Jaeckle, H., Schaefer, U. (2004). Systematic gene targeting on the X chromosome of Drosophila melanogaster.  Chromosoma 113(6): 271--275. (Export to RIS)
FlyBase ID FBrf0183806
Publication Type Research paper
PubMed ID 15480728
PubMed Abstract The genome of the model organism Drosophila melanogaster has been sequenced and annotated. Based on this groundwork, we performed a systematic genetic screen of the D. melanogaster X chromosome, which carries about one sixth of the genes of the organism. We generated a collection of single P-element insertions to provide genetic and molecular access to virtually all X-chromosomal genes. The study complements earlier work designed to systematically identify vital genes on the X chromosome by targeting transcription units which are phenotypically silent. We describe single UAS sequence-bearing P-element insertions throughout the X chromosome, which allows one to express the tagged genes under control of tissue/organ-directed GAL4 activity. In addition, the present collection of single insertion lines provides a tool to generate chromosomal deletions which are on average less than 33 kb in size.
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Language of Publication English
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Publication Type Journal
Abbreviation Chromosoma
Title Chromosoma
Publication Year 1939-
ISBN/ISSN 0009-5915
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