Reference Report
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| Citation | Beinert, N., Werner, M., Dowe, G., Chung, H.R., Jaeckle, H., Schaefer, U. (2004). Systematic gene targeting on the X chromosome of Drosophila melanogaster. Chromosoma 113(6): 271--275. (Export to RIS) | ||
| FlyBase ID | FBrf0183806 | ||
| Publication Type | Research paper | ||
| PubMed ID | 15480728 | ||
| PubMed Abstract | The genome of the model organism Drosophila melanogaster has been sequenced and annotated. Based on this groundwork, we performed a systematic genetic screen of the D. melanogaster X chromosome, which carries about one sixth of the genes of the organism. We generated a collection of single P-element insertions to provide genetic and molecular access to virtually all X-chromosomal genes. The study complements earlier work designed to systematically identify vital genes on the X chromosome by targeting transcription units which are phenotypically silent. We describe single UAS sequence-bearing P-element insertions throughout the X chromosome, which allows one to express the tagged genes under control of tissue/organ-directed GAL4 activity. In addition, the present collection of single insertion lines provides a tool to generate chromosomal deletions which are on average less than 33 kb in size. | ||
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| Language of Publication | English | ||
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| Publication Type | Journal | ||
| Abbreviation | Chromosoma | ||
| Title | Chromosoma | ||
| Publication Year | 1939- | ||
| ISBN/ISSN | 0009-5915 | ||
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Genes (1)
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