A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Reference Report

Reference
Citation Briscoe, J., Therond, P. (2005). Hedgehog signaling: from the Drosophila cuticle to anti-cancer drugs.  Dev. Cell 8(2): 143--151. (Export to RIS)
FlyBase ID FBrf0183872
Publication Type Conference report
PubMed ID 15736317
PubMed Abstract Hh signaling controls cell proliferation and differentiation in processes that range from insect segmentation and limb formation to vertebrate neural tube development and bone differentiation. Moreover, Hh signaling appears to regulate stem cell homeostasis in adult tissues, while persistent Hh pathway activity has pathological consequences in a number of cancers. Two recent meetings, a Karolinska Institute Nobel conference (August 22-24, 2004) and a joint EMBO and Juan March Institute workshop (October 25-27, 2004), provided the opportunity to take stock of the progress that has been made in understanding Hh signaling and also to remind us of the many questions that still remain unanswered.
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Language of Publication English
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Publication Type Journal
Abbreviation Dev. Cell
Title Developmental Cell
Publication Year 2001-
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