|Citation||Ray, P.S., Fox, P.L. (2005). Equality of the sexes: found in translation. Cell 122(4): 492--493. (Export to RIS)|
|PubMed Abstract||Male fruit flies (and humans) have half the number of X chromosomes that females have, yet the expression of X-linked proteins in males is the same because of a sex-specific compensatory mechanism. In this issue of Cell, report that a unique two-stage translation silencing mechanism thwarts synthesis of a male-specific transcription activator in female flies, ensuring that gene dosage compensation occurs only in males.|
|Research paper||A dual inhibitory mechanism restricts msl-2 mRNA translation for dosage compensation in Drosophila.
Beckmann et al., 2005, Cell 122(4): 529--540 [FBrf0187219]
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|Language of Publication||English|
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