Reference Report

Reference
Citation	Ray, P.S., Fox, P.L. (2005). Equality of the sexes: found in translation. Cell 122(4): 492--493. (Export to RIS)
FlyBase ID	FBrf0187234
Publication Type	Review
PubMed ID	16122416
PubMed Abstract	Male fruit flies (and humans) have half the number of X chromosomes that females have, yet the expression of X-linked proteins in males is the same because of a sex-specific compensatory mechanism. In this issue of Cell, report that a unique two-stage translation silencing mechanism thwarts synthesis of a male-specific transcription activator in female flies, ensuring that gene dosage compensation occurs only in males.
DOI
Related Publication(s)
Research paper	A dual inhibitory mechanism restricts msl-2 mRNA translation for dosage compensation in Drosophila. Beckmann et al., 2005, Cell 122(4): 529--540 [FBrf0187219]
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Secondary IDs
Language of Publication	English
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Also Published As
Parent Publication
Publication Type	Journal
Abbreviation	Cell
Title	Cell
Publication Year	1974-
ISBN/ISSN	0092-8674
Data from Reference
Genes (7)
	mle mof msl-1 msl-2 roX1 roX2 Sxl