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Citation
Ray, P.S., Fox, P.L. (2005). Equality of the sexes: found in translation.  Cell 122(4): 492--493.
FlyBase ID
FBrf0187234
Publication Type
Note
Abstract
Male fruit flies (and humans) have half the number of X chromosomes that females have, yet the expression of X-linked proteins in males is the same because of a sex-specific compensatory mechanism. In this issue of Cell, report that a unique two-stage translation silencing mechanism thwarts synthesis of a male-specific transcription activator in female flies, ensuring that gene dosage compensation occurs only in males.
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PubMed Central ID
Related Publication(s)
Research paper
A dual inhibitory mechanism restricts msl-2 mRNA translation for dosage compensation in Drosophila.
Beckmann et al., 2005, Cell 122(4): 529--540 [FBrf0187219]
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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Cell
    Title
    Cell
    Publication Year
    1974-
    ISBN/ISSN
    0092-8674
    Data From Reference
    Genes (7)