|Citation||Aminetzach, Y.T., Macpherson, J.M., Petrov, D.A. (2005). Pesticide resistance via transposition-mediated adaptive gene truncation in Drosophila. Science 309(5735): 764--767. (Export to RIS)|
|Publication Type||Research paper|
|PubMed Abstract||To study adaptation, it is essential to identify multiple adaptive mutations and to characterize their molecular, phenotypic, selective, and ecological consequences. Here we describe a genomic screen for adaptive insertions of transposable elements in Drosophila. Using a pilot application of this screen, we have identified an adaptive transposable element insertion, which truncates a gene and apparently generates a functional protein in the process. The insertion of this transposable element confers increased resistance to an organophosphate pesticide and has spread in D. melanogaster recently.|
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|Language of Publication||English|
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|Data from Reference|
|Natural transposons (1)|