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| Citation | Aminetzach, Y.T., Macpherson, J.M., Petrov, D.A. (2005). Pesticide resistance via transposition-mediated adaptive gene truncation in Drosophila. Science 309(5735): 764--767. (Export to RIS) | ||
| FlyBase ID | FBrf0188316 | ||
| Publication Type | Research paper | ||
| PubMed ID | 16051794 | ||
| PubMed Abstract | To study adaptation, it is essential to identify multiple adaptive mutations and to characterize their molecular, phenotypic, selective, and ecological consequences. Here we describe a genomic screen for adaptive insertions of transposable elements in Drosophila. Using a pilot application of this screen, we have identified an adaptive transposable element insertion, which truncates a gene and apparently generates a functional protein in the process. The insertion of this transposable element confers increased resistance to an organophosphate pesticide and has spread in D. melanogaster recently. | ||
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| Language of Publication | English | ||
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| Publication Type | Journal | ||
| Abbreviation | Science | ||
| Title | Science | ||
| Publication Year | 1895- | ||
| ISBN/ISSN | 0036-8075 | ||
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Data from Reference
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| Alleles (1)
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| Genes (5)
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| Natural transposons (1)
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