|Citation||Giebel, B., Wodarz, A. (2006). Tumor suppressors: control of signaling by endocytosis. Curr. Biol. 16(3): R91--R92. (Export to RIS)|
|PubMed Abstract||Genetic defects of the endosomal 'ESCRT' machinery in Drosophila have been found to cause loss of epithelial cell polarity, accompanied by overproliferation of mutant and adjacent wild-type cells. These results can be attributed to defective endocytosis of transmembrane proteins that control cell polarity and proliferation, including Crumbs and Notch.|
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|Language of Publication||English|
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