Reference Report

Reference
Citation	Alexander, S.J., Woodling, N.S., Yedvobnick, B. (2006). Insertional inactivation of the L13a ribosomal protein gene of Drosophila melanogaster identifies a new Minute locus. Gene 368(): 46--52. (Export to RIS)
FlyBase ID	FBrf0190498
Publication Type	Research paper
External Crossreferences
PubMed ID	16326033
PubMed Abstract	We have utilized a transposable P element construct to scan the genome for modifiers of Drosophila Notch pathway phenotypes. From a collection of 2000 inserts we obtained two enhancers and one suppressor. Sequence analysis of the insertion regions demonstrated that two modifiers affect known components of the Notch pathway, whereas the third is an insert in the gene encoding ribosomal protein L13a at cytogenetic region 83B6-7. The insert in the RpL13A coding region creates a classic Minute mutation which enhances Notch pathway wing phenotypes. This report adds RpL13A to the list of Drosophila ribosomal protein genes that cause Minute phenotypes when mutated.
BIOSIS ID	2006.328739
Zoological Record ID
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Secondary IDs
Language of Publication	English
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ISBN
Parent Publication
Publication Type	Journal
Abbreviation	Gene
Title	Gene
Editors
Publication Year	1976-
ISBN/ISSN	0378-1119
Data from Reference
Alleles (12)
	Dl^EP3816.A Dl^unspecified mam^EP2022.A mam^H.Scer\UAS mam^N.Scer\UAS mam^Scer\UAS.cAa N^nd-1 peb^EP55 RpL13A^EP3614.A Scer\GAL4³⁰⁹ Scer\GAL4^bbg-C96 Scer\GAL4^pnr-MD237
Constructs (4)
	P{EP} P{UAS-mam.A} P{UAS-mamH} P{UAS-mamN}
Genes (7)
	Dl eve mam N peb RpL13A Scer\GAL4
Insertions (6)
	P{EP}Dl^EP3816.A P{EP}mam^EP2022.A P{EP}RpL13A^EP3614.A P{GAL4}309 P{GawB}bbg^C96 P{GawB}pnr^MD237
Natural transposons (1)
	P-element