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Citation
Wilson, C.W., Chuang, P.T. (2006). New "hogs" in hedgehog transport and signal reception.  Cell 125(3): 435--438.
FlyBase ID
FBrf0193246
Publication Type
Review
Abstract
A recent paper in Cell (Yao et al., 2006) and two papers in Developmental Cell (Tenzen et al., 2006; Zhang et al., 2006) identify a new receptor component for Hedgehog, a key morphogen in embryonic development. Many other proteins that bind to Hedgehog in the extracellular matrix or on the cell surface have been identified. In light of these recent discoveries, we discuss how these factors control the stability, transport, reception, and availability of Hedgehog in modulating Hedgehog-mediated responses.
PubMed ID
PubMed Central ID
Related Publication(s)
Research paper
The ihog cell-surface proteins bind Hedgehog and mediate pathway activation.
Yao et al., 2006, Cell 125(2): 343--357 [FBrf0189929]
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Secondary IDs
  • FBrf0199180
Language of Publication
English
Additional Languages of Abstract
Parent Publication
Publication Type
Journal
Abbreviation
Cell
Title
Cell
Publication Year
1974-
ISBN/ISSN
0092-8674
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Genes (14)