Reference Report

Reference
Citation	Stahl, M., Schuh, R., Adryan, B. (2007). Identification of FGF-dependent genes in the Drosophila tracheal system. Gene Expr. Patterns 7(1-2): 202--209. (Export to RIS)
FlyBase ID	FBrf0193395
Publication Type	Research paper
PubMed ID	16949886
PubMed Abstract	The embryonic development of the tracheal system of the fruit fly Drosophila provides a paradigm for genetic studies of branching morphogenesis. Efforts of many laboratories have identified Branchless (Bnl, a fibroblast growth factor homologue) and Breathless (Btl, the receptor homologue) as crucial factors at many stages of tracheal system development. The downstream targets of the Bnl/Btl signalling cascade, however, remain mostly unknown. Misexpression of the bnl gene results in specific tracheal phenotypes that lead to larval death. We characterised the transcriptional profiles of targeted over-expression of bnl in the embryonic trachea and of loss-of-function bnl(P1) mutant embryos. Gene expression data was mapped to high-throughput in situ hybridisation based ImaGO-annotation. Thus, we identified and confirmed by quantitative PCR 13 Bnl-dependent genes that are expressed in cells within and outside of the tracheal system.
DOI	10.1016/j.modgep.2006.07.005
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Language of Publication	English
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Publication Type	Journal
Abbreviation	Gene Expr. Patterns
Title	Gene expression patterns : GEP
Publication Year	2002-
ISBN/ISSN	1567-133X 1872-7298
Data from Reference
Alleles (5)
	bnl⁰⁰⁸⁵⁷ bnl^Scer\UAS.cSa btl^{activ.Scer\UAS} Ecol\lacZ^trh-1-eve-1 Scer\GAL4^btl.PS
Constructs (3)
	P{GAL4-btl.S} P{UAS-bnl.S} P{UAS-btl.activ}
Genes (28)
	bnl bs btl Cda4 CG4115 CG14569 CG15065 CG15067 CG15068 CG16836 CG18107 CG42749 Cpr51A Cpr64Ad Ecol\lacZ for Gasp IM1 IM2 IM3 IM10 IM23 kuk obst-A Scer\GAL4 serp Stat92E β-Spec
Insertions (1)
	P{ET-L}trh-1-eve-1
Natural transposons (1)
	P-element