|Citation||Stahl, M., Schuh, R., Adryan, B. (2007). Identification of FGF-dependent genes in the Drosophila tracheal system. Gene Expr. Patterns 7(1-2): 202--209. (Export to RIS)|
|Publication Type||Research paper|
|PubMed Abstract||The embryonic development of the tracheal system of the fruit fly Drosophila provides a paradigm for genetic studies of branching morphogenesis. Efforts of many laboratories have identified Branchless (Bnl, a fibroblast growth factor homologue) and Breathless (Btl, the receptor homologue) as crucial factors at many stages of tracheal system development. The downstream targets of the Bnl/Btl signalling cascade, however, remain mostly unknown. Misexpression of the bnl gene results in specific tracheal phenotypes that lead to larval death. We characterised the transcriptional profiles of targeted over-expression of bnl in the embryonic trachea and of loss-of-function bnl(P1) mutant embryos. Gene expression data was mapped to high-throughput in situ hybridisation based ImaGO-annotation. Thus, we identified and confirmed by quantitative PCR 13 Bnl-dependent genes that are expressed in cells within and outside of the tracheal system.|
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|Language of Publication||English|
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|Also Published As|
|Abbreviation||Gene Expr. Patterns|
|Title||Gene expression patterns : GEP|
|Data from Reference|
|Natural transposons (1)|