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Citation
Winter, V., Hauser, M.T. (2006). Exploring the ESCRTing machinery in eukaryotes.  Trends Plant Sci. 11(3): 115--123.
FlyBase ID
FBrf0195071
Publication Type
Review
Abstract
The profile of protein sorting into multivesicular bodies (MVBs) has risen recently with the identification of three heteromeric complexes known as ESCRT-I,-II,-III (Endosomal Sorting Complex Required for Transport). Genetic analyses in yeast have identified up to 15 soluble class E VPS (vacuolar protein sorting) proteins that have been assigned to the ESCRT machinery and function in cargo recognition and sorting, complex assembly, vesicle formation and dissociation. Despite their functional importance in yeast and mammalian cells, little is known about their presence and function in other organisms including plants. We have made use of the fully sequenced genomes of Arabidopsis thaliana and Oryza sativa, Drosophila melanogaster and Caenorhabditis elegans to explore the identity, structural characteristics and phylogenetic relationships of proteins assigned to the ESCRT machinery.
PubMed ID
PubMed Central ID
PMC2865992 (PMC) (EuropePMC)
Associated Information
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Secondary IDs
  • FBrf0190659
Language of Publication
English
Additional Languages of Abstract
Parent Publication
Publication Type
Compendium
Abbreviation
Trends Plant Sci.
Title
Trends in Plant Science
Publication Year
1996-
ISBN/ISSN
1366-2570
Data From Reference
Genes (10)