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Reference Report
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| Citation | Straub, T., Becker, P.B. (2007). Dosage compensation: the beginning and end of generalization. Nat. Rev. Genet. 8(1): 47--57. (Export to RIS) | ||
| FlyBase ID | FBrf0195275 | ||
| Publication Type | Review | ||
| PubMed ID | 17173057 | ||
| PubMed Abstract | The genomes of higher eukaryotes are carefully balanced systems of gene expression that compensate for the different numbers of sex chromosomes in the two sexes by adjusting gene expression levels. Different strategies for sex chromosome dosage compensation have evolved, which all involve modulating chromatin structure as a means to fine-tune transcription levels. As data accumulate, previous over-simplifications are being revised, and novel features of the compensation processes are gaining attention, many of which are of sufficient global validity to influence our view on gene expression beyond the realm of dosage compensation itself. | ||
| DOI | 10.1038/nrg2013 | ||
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| FB2013_03 | |||
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| All updates | Click here to see a list of all updates to this record from FB2010_08 and on. | ||
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| Language of Publication | English | ||
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| Publication Type | Journal | ||
| Abbreviation | Nat. Rev. Genet. | ||
| Title | Nature Reviews. Genetics | ||
| Publication Year | 2000- | ||
| ISBN/ISSN | 1471-0056 1471-0064 | ||
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Data from Reference
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| Genes (18)
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