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Drosophila 12 Genomes Consortium, Clark, A.G., Eisen, M.B., Smith, D.R., Bergman, C.M., Oliver, B., Markow, T.A., Kaufman, T.C., Kellis, M., Gelbart, W., Iyer, V.N., Pollard, D.A., Sackton, T.B., Larracuente, A.M., Singh, N.D., Abad, J.P., Abt, D.N., Adryan, B., Aguade, M., Akashi, H., Anderson, W.W., Aquadro, C.F., Ardell, D.H., Arguello, R., Artieri, C.G., Barbash, D.A., Barker, D., Barsanti, P., Batterham, P., Batzoglou, S., Begun, D., Bhutkar, A., Blanco, E., Bosak, S.A., Bradley, R.K., Brand, A.D., Brent, M.R., Brooks, A.N., Brown, R.H., Butlin, R.K., Caggese, C., Calvi, B.R., Bernardo de Carvalho, A., Caspi, A., Castrezana, S., Celniker, S.E., Chang, J.L., Chapple, C., Chatterji, S., Chinwalla, A., Civetta, A., Clifton, S.W., Comeron, J.M., Costello, J.C., Coyne, J.A., Daub, J., David, R.G., Delcher, A.L., Delehaunty, K., Do, C.B., Ebling, H., Edwards, K., Eickbush, T., Evans, J.D., Filipski, A., FindeiƟ, S., Freyhult, E., Fulton, L., Fulton, R., Garcia, A.C., Gardiner, A., Garfield, D.A., Garvin, B.E., Gibson, G., Gilbert, D., Gnerre, S., Godfrey, J., Good, R., Gotea, V., Gravely, B., Greenberg, A.J., Griffiths-Jones, S., Gross, S., Guigo, R., Gustafson, E.A., Haerty, W., Hahn, M.W., Halligan, D.L., Halpern, A.L., Halter, G.M., Han, M.V., Heger, A., Hillier, L., Hinrichs, A.S., Holmes, I., Hoskins, R.A., Hubisz, M.J., Hultmark, D., Huntley, M.A., Jaffe, D.B., Jagadeeshan, S., Jeck, W.R., Johnson, J., Jones, C.D., Jordan, W.C., Karpen, G.H., Kataoka, E., Keightley, P.D., Kheradpour, P., Kirkness, E.F., Koerich, L.B., Kristiansen, K., Kudrna, D., Kulathinal, R.J., Kumar, S., Kwok, R., Lander, E., Langley, C.H., Lapoint, R., Lazzaro, B.P., Lee, S.J., Levesque, L., Li, R., Lin, C.F., Lin, M.F., Lindblad-Toh, K., Llopart, A., Long, M., Low, L., Lozovsky, E., Lu, J., Luo, M., Machado, C.A., Makalowski, W., Marzo, M., Matsuda, M., Matzkin, L., McAllister, B., McBride, C.S., McKernan, B., McKernan, K., Mendez-Lago, M., Minx, P., Mollenhauer, M.U., Montooth, K., Mount, S.M., Mu, X., Myers, E., Negre, B., Newfeld, S., Nielsen, R., Noor, M.A., O'Grady, P., Pachter, L., Papaceit, M., Parisi, M.J., Parisi, M., Parts, L., Pedersen, J.S., Pesole, G., Phillippy, A.M., Ponting, C.P., Pop, M., Porcelli, D., Powell, J.R., Prohaska, S., Pruitt, K., Puig, M., Quesneville, H., Ram, K.R., Rand, D., Rasmussen, M.D., Reed, L.K., Reenan, R., Reily, A., Remington, K.A., Rieger, T.T., Ritchie, M.G., Robin, C., Rogers, Y.H., Rohde, C., Rozas, J., Rubenfield, M.J., Ruiz, A., Russo, S., Salzberg, S.L., Sanchez-Gracia, A., Saranga, D.J., Sato, H., Schaeffer, S.W., Schatz, M.C., Schlenke, T., Schwartz, R., Segarra, C., Singh, R.S., Sirot, L., Sirota, M., Sisneros, N.B., Smith, C.D., Smith, T.F., Spieth, J., Stage, D.E., Stark, A., Stephan, W., Strausberg, R.L., Strempel, S., Sturgill, D., Sutton, G., Sutton, G.G., Tao, W., Teichmann, S., Tobari, Y.N., Tomimura, Y., Tsolas, J.M., Valente, V.L., Venter, E., Venter, J.C., Vicario, S., Vieira, F.G., Vilella, A.J., Villasante, A., Walenz, B., Wang, J., Wasserman, M., Watts, T., Wilson, D., Wilson, R.K., Wing, R.A., Wolfner, M.F., Wong, A., Wong, G.K., Wu, C.I., Wu, G., Yamamoto, D., Yang, H.P., Yang, S.P., Yorke, J.A., Yoshida, K., Zdobnov, E., Zhang, P., Zhang, Y., Zimin, A.V., Baldwin, J., Abdouelleil, A., Abdulkadir, J., Abebe, A., Abera, B., Abreu, J., Acer, S.C., Aftuck, L., Alexander, A., An, P., Anderson, E., Anderson, S., Arachi, H., Azer, M., Bachantsang, P., Barry, A., Bayul, T., Berlin, A., Bessette, D., Bloom, T., Blye, J., Boguslavskiy, L., Bonnet, C., Boukhgalter, B., Bourzgui, I., Brown, A., Cahill, P., Channer, S., Cheshatsang, Y., Chuda, L., Citroen, M., Collymore, A., Cooke, P., Costello, M., D'Aco, K., Daza, R., De Haan, G., DeGray, S., DeMaso, C., Dhargay, N., Dooley, K., Dooley, E., Doricent, M., Dorje, P., Dorjee, K., Dupes, A., Elong, R., Falk, J., Farina, A., Faro, S., Ferguson, D., Fisher, S., Foley, C.D., Franke, A., Friedrich, D., Gadbois, L., Gearin, G., Gearin, C.R., Giannoukos, G., Goode, T., Graham, J., Grandbois, E., Grewal, S., Gyaltsen, K., Hafez, N., Hagos, B., Hall, J., Henson, C., Hollinger, A., Honan, T., Huard, M.D., Hughes, L., Hurhula, B., Husby, M.E., Kamat, A., Kanga, B., Kashin, S., Khazanovich, D., Kisner, P., Lance, K., Lara, M., Lee, W., Lennon, N., Letendre, F., LeVine, R., Lipovsky, A., Liu, X., Liu, J., Liu, S., Lokyitsang, T., Lokyitsang, Y., Lubonja, R., Lui, A., MacDonald, P., Magnisalis, V., Maru, K., Matthews, C., McCusker, W., McDonough, S., Mehta, T., Meldrim, J., Meneus, L., Mihai, O., Mihalev, A., Mihova, T., Mittelman, R., Mlenga, V., Montmayeur, A., Mulrain, L., Navidi, A., Naylor, J., Negash, T., Nguyen, T., Nguyen, N., Nicol, R., Norbu, C., Norbu, N., Novod, N., O'Neill, B., Osman, S., Markiewicz, E., Oyono, O.L., Patti, C., Phunkhang, P., Pierre, F., Priest, M., Raghuraman, S., Rege, F., Reyes, R., Rise, C., Rogov, P., Ross, K., Ryan, E., Settipalli, S., Shea, T., Sherpa, N., Shi, L., Shih, D., Sparrow, T., Spaulding, J., Stalker, J., Stange-Thomann, N., Stavropoulos, S., Stone, C., Strader, C., Tesfaye, S., Thomson, T., Thoulutsang, Y., Thoulutsang, D., Topham, K., Topping, I., Tsamla, T., Vassiliev, H., Vo, A., Wangchuk, T., Wangdi, T., Weiand, M., Wilkinson, J., Wilson, A., Yadav, S., Young, G., Yu, Q., Zembek, L., Zhong, D., Zimmer, A., Zwirko, Z., Jaffe, D.B., Alvarez, P., Brockman, W., Butler, J., Chin, C., Gnerre, S., Grabherr, M., Kleber, M., Mauceli, E., MacCallum, I. (2007). Evolution of genes and genomes on the Drosophila phylogeny.  Nature 450(7167): 203--218.
FlyBase ID
FBrf0200326
Publication Type
Research paper
Abstract
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves the precision and sensitivity of evolutionary inference, producing more robust results than single-genome analyses can provide. The genomes of 12 Drosophila species, ten of which are presented here for the first time (sechellia, simulans, yakuba, erecta, ananassae, persimilis, willistoni, mojavensis, virilis and grimshawi), illustrate how rates and patterns of sequence divergence across taxa can illuminate evolutionary processes on a genomic scale. These genome sequences augment the formidable genetic tools that have made Drosophila melanogaster a pre-eminent model for animal genetics, and will further catalyse fundamental research on mechanisms of development, cell biology, genetics, disease, neurobiology, behaviour, physiology and evolution. Despite remarkable similarities among these Drosophila species, we identified many putatively non-neutral changes in protein-coding genes, non-coding RNA genes, and cis-regulatory regions. These may prove to underlie differences in the ecology and behaviour of these diverse species.
PubMed ID
PubMed Central ID
Related Publication(s)
Personal communication to FlyBase
Symbols and class of gene information for the GLEANR consensus sequences of the 11 sequenced non-melanogaster Drosophila species (Drosophila ananassae, erecta, grimshawi, mojavensis, persimilis, pseudoobscura, sechellia, simulans, willistoni, virilis and yakuba).
Drosophila 12 Genomes Consortium, 2008, personal communication to FlyBase [FBrf0202436]
FlyBase analysis
Associations of D. pseudoobscura GLEANR gene predictions (Release 2.1) with previously known genes in FlyBase.
FlyBase, 2008, Associations of D. pseudoobscura GLEANR gene predictions (Release 2.1) with previously known genes in FlyBase. [FBrf0202438]
Newly sequenced Drosophila genomes: associations of GLEANR gene predictions (Releases 1.0) with previously known genes in FlyBase.
FlyBase, 2008, Newly sequenced Drosophila genomes: associations of GLEANR gene predictions (Releases 1.0) with previously known genes in FlyBase. [FBrf0202439]
Note
Evolutionary genomics: come fly with us.
Birney, 2007, Nature 450(7167): 184--185 [FBrf0202433]
Associated Information
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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Nature
    Title
    Nature
    Publication Year
    1869-
    ISBN/ISSN
    0028-0836
    Data From Reference
    Genes (173980)