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Citation
Torok, T., Benitez, C., Takacs, S., Biessmann, H. (2007). The protein encoded by the gene proliferation disrupter (prod) is associated with the telomeric retrotransposon array in Drosophila melanogaster.  Chromosoma 116(2): 185--195.
FlyBase ID
FBrf0201264
Publication Type
Research paper
Abstract

We report in this paper that the PROD protein, encoded by the gene proliferation disrupter (prod), is associated with the telomeric chromatin in Drosophila melanogaster. It binds to a region just upstream of the promoter of the telomere-specific retrotransposon HeT-A, which is located in the long 3'untranslated region of the element near its oligo(A) tail. Reduction of PROD in prod heterozygote flies results in elevated levels of HeT-A RNA in the ovaries, suggesting that PROD functions as a repressor of HeT-A transcriptional activity at the telomeres.

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Secondary IDs
  • FBrf0194375
Language of Publication
English
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Parent Publication
Publication Type
Journal
Abbreviation
Chromosoma
Title
Chromosoma
Publication Year
1939-
ISBN/ISSN
0009-5915
Data From Reference
Genes (1)
Natural transposons (1)