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Zhang, K., Guo, J.Z., Peng, Y., Xi, W., Guo, A. (2007). Dopamine-mushroom body circuit regulates saliency-based decision-making in Drosophila.  Science 316(5833): 1901--1904.
FlyBase ID
FBrf0202219
Publication Type
Research paper
Abstract

Drosophila melanogaster can make appropriate choices among alternative flight options on the basis of the relative salience of competing visual cues. We show that this choice behavior consists of early and late phases; the former requires activation of the dopaminergic system and mushroom bodies, whereas the latter is independent of these activities. Immunohistological analysis showed that mushroom bodies are densely innervated by dopaminergic axons. Thus, the circuit from the dopamine system to mushroom bodies is crucial for choice behavior in Drosophila.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Science
    Title
    Science
    Publication Year
    1895-
    ISBN/ISSN
    0036-8075
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