A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

Reference Report

Reference
Citation FlyBase Curators, (2008). Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations.  (Export to RIS)
FlyBase ID FBrf0202955
Publication Type FlyBase analysis
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Description
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
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This section does not currently display links that were removed or gene model changes.
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Comments
Information attributed to this reference entered the database in the course of FlyBase stock curation. FlyBase nomenclature rules currently recommend that the name of an insertion of a recombinant construct incorporate an allele symbol as the insertion identifier when an insertion is within the annotated transcription unit of a gene. In the absence of data supporting disruption of a specific gene's function, an insertion that is outside any annotated transcription unit is not considered to cause an allele. Thus, changes in either gene annotations or insertion map locations can have consequences for the symbols of insertions, and for the existence of alleles. Four kinds of changes to FlyBase records can result from reanalysis of gene annotations or insertion map data:
1. Insertions named with a line identifier or other arbitrary symbol are renamed using an allele symbol as the insertion identifier. For example, P{SUPor-P}KG06996 was renamed P{SUPor-P}Rtnl1[KG06996] in the course of FlyBase curation.
2. Insertions named with an allele symbol are renamed using a line identifier or other arbitrary symbol. For example, PBac{PB}CG6069[c05699] was renamed PBac{PB}c05699 in the course of FlyBase curation.
3. New alleles are created for genes that are physically disrupted by an insertion (defined as an insertion within the annotated transcription unit). For example, Rtnl1[KG06996] was created in the course of FlyBase curation.
4. Existing alleles are eliminated if an insertion does not physically disrupt a gene and there is no evidence for functional disruption of a specific gene. For example, CG6069[c05699] was eliminated in the course of FlyBase curation.
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Language of Publication English
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