Reference Report

Reference
Citation	Dankert, H., Wang, L., Hoopfer, E.D., Anderson, D.J., Perona, P. (2009). Automated monitoring and analysis of social behavior in Drosophila. Nat. Methods 6(4): 297--303. (Export to RIS)
FlyBase ID	FBrf0207671
Publication Type	Research paper
PubMed ID	19270697
PubMed Abstract	We introduce a method based on machine vision for automatically measuring aggression and courtship in Drosophila melanogaster. The genetic and neural circuit bases of these innate social behaviors are poorly understood. High-throughput behavioral screening in this genetically tractable model organism is a potentially powerful approach, but it is currently very laborious. Our system monitors interacting pairs of flies and computes their location, orientation and wing posture. These features are used for detecting behaviors exhibited during aggression and courtship. Among these, wing threat, lunging and tussling are specific to aggression; circling, wing extension (courtship 'song') and copulation are specific to courtship; locomotion and chasing are common to both. Ethograms may be constructed automatically from these measurements, saving considerable time and effort. This technology should enable large-scale screens for genes and neural circuits controlling courtship and aggression.
DOI	10.1038/nmeth.1310
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Language of Publication	English
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Publication Type	Journal
Abbreviation	Nat. Methods
Title	Nature Methods
Publication Year	2004-
ISBN/ISSN	1548-7091 1548-7105
Data from Reference
Alleles (5)
	fru^F Hsap\KCNJ2^{Scer\UAS.T:Avic\GFP-EGFP} Scer\GAL4^Cha.7.4 Scer\GAL4^Tdc2.PC tra^Scer\UAS.cFa
Constructs (4)
	P{Cha-GAL4.7.4} P{Tdc2-GAL4.C} P{UAS-Hsap\KCNJ2.EGFP} P{UAS-tra.F}
Genes (5)
	fru Hsap\KCNJ2 Scer\GAL4 Tdc2 tra