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Citation
Fisher, K.H., Deane, C.M., Wakefield, J.G. (2008). The functional domain grouping of microtubule associated proteins.  Commun. Integr. Biol. 1(1): 47--50.
FlyBase ID
FBrf0208562
Publication Type
Research paper
Abstract
Microtubules (MTs), which play crucial roles in normal cell function, are regulated by MT associated proteins (MAPs). Using a combinatorial approach that includes biochemistry, proteomics and bioinformatics, we have recently identified 270 putative MAPs from Drosophila embryos and characterized some of those required for correct progression through mitosis. Here we identify functional groups of these MAPs using a reciprocal hits sequence alignment technique and assign InterPro functional domains to 28 previously uncharacterized proteins. This approach gives insight into the potential functions of MAPs and how their roles may affect MTs.
PubMed ID
PubMed Central ID
PMC2633798 (PMC) (EuropePMC)
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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Commun. Integr. Biol.
    Title
    Communicative & integrative biology
    ISBN/ISSN
    1942-0889
    Data From Reference