Reference Report

Reference
Citation	Andreyenkova, N.G., Kokoza, E.B., Semeshin, V.F., Belyaeva, E.S., Demakov, S.A., Pindyurin, A.V., Andreyeva, E.N., Volkova, E.I., Zhimulev, I.F. (2009). Localization and characteristics of DNA underreplication zone in the 75C region of intercalary heterochromatin in Drosophila melanogaster polytene chromosomes. Chromosoma 118(6): 747--761. (Export to RIS)
FlyBase ID	FBrf0209251
Publication Type	Research paper
PubMed ID	19685068
PubMed Abstract	In Drosophila polytene chromosomes, regions of intercalary heterochromatin are scattered throughout the euchromatic arms. Here, we present data on the first fine analysis of the individual intercalary heterochromatin region, 75C1-2, located in the 3L chromosome. By using electron microscopy, we demonstrated that this region appears as three closely adjacent condensed bands. Mapping of the region on the physical map by means of the chromosomal rearrangements with known breakpoints showed that the length of the region is about 445 kb. Although it seems that the SUUR protein binds to the whole 75C1-2 region, the proximal part of the region is fully polytenized, so the DNA underreplication zone is asymmetric and located in the distal half of the region. Finally, we speculate that intercalary heterochromatin regions of Drosophila polytene chromosomes are organized into three different types with respect to the localization of the underreplication zone.
DOI	10.1007/s00412-009-0232-6
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Language of Publication	English
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Publication Type	Journal
Abbreviation	Chromosoma
Title	Chromosoma
Publication Year	1939-
ISBN/ISSN	0009-5915
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	SuUR