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Citation
Kwon, Y., Shen, W.L., Shim, H.S., Montell, C. (2010). Fine Thermotactic Discrimination between the Optimal and Slightly Cooler Temperatures via a TRPV Channel in Chordotonal Neurons.  J. Neurosci. 30(31): 10465--10471.
FlyBase ID
FBrf0211446
Publication Type
Research paper
Abstract

Animals select their optimal environmental temperature, even when faced with alternatives that differ only slightly. This behavior is critical as small differences in temperature of only several degrees can have a profound effect on the survival and rate of development of poikilothermic animals, such as the fruit fly. Here, we demonstrate that Drosophila larvae choose their preferred temperature of 17.5 degrees C over slightly cooler temperatures (14-16 degrees C) through activation of chordotonal neurons. Mutations affecting a transient receptor potential (TRP) vanilloid channel, Inactive (Iav), which is expressed specifically in chordotonal neurons, eliminated the ability to choose 17.5 degrees C over 14-16 degrees C. The impairment in selecting 17.5 degrees C resulted from absence of an avoidance response, which is normally mediated by an increase in turns at the lower temperatures. We conclude that the decision to select the preferred over slightly cooler temperatures requires iav and is achieved by activating chordotonal neurons, which in turn induces repulsive behaviors, due to an increase in high angle turns.

PubMed ID
PubMed Central ID
PMC3335392 (PMC) (EuropePMC)
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Secondary IDs
    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    J. Neurosci.
    Title
    Journal of Neuroscience
    Publication Year
    1981-
    ISBN/ISSN
    0270-6474 1529-2401
    Data From Reference