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Citation
Gong, Z., Liu, J., Guo, C., Zhou, Y., Teng, Y., Liu, L. (2010). Two pairs of neurons in the central brain control Drosophila innate light preference.  Science 330(6003): 499--502.
FlyBase ID
FBrf0212127
Publication Type
Research paper
Abstract
Appropriate preferences for light or dark conditions can be crucial for an animal's survival. Innate light preferences are not static in some animals, including the fruit fly Drosophila melanogaster, which prefers darkness in the feeding larval stage but prefers light in adulthood. To elucidate the neural circuit underlying light preference, we examined the neurons involved in larval phototactic behavior by regulating neuronal functions. Modulating activity of two pairs of isomorphic neurons in the central brain switched the larval light preference between photophobic and photophilic. These neurons were found to be immediately downstream of pdf-expressing lateral neurons, which are innervated by larval photoreceptors. Our results revealed a neural mechanism that could enable the adjustment of animals' response strategies to environmental stimuli according to biological needs.
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Related Publication(s)
Note
Developmental biology. Flipping the light switch.
Vogt and Desplan, 2010, Science 330(6003): 454--455 [FBrf0214146]
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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Science
    Title
    Science
    Publication Year
    1895-
    ISBN/ISSN
    0036-8075
    Data From Reference