Reference Report

Reference
Citation	Yurlova, A.A., Makunin, I.V., Zhimulev, I.F. (2010). [Phylogenetic analysis of the rapidly evolving SuUR gene in insects]. Genetika, Moscow 46(9): 1272--1275. (Export to RIS)
FlyBase ID	FBrf0212293
Publication Type	Research paper
PubMed ID	21061633
PubMed Abstract	Different genome regions differ in replication timing during the S phase. Late-replicating sequences are often underreplicated in the Drosophila salivary-gland polytene chromosomes. The SuUR gene, whose mutation changes the replication time of late-replicating regions in salivary-gland cells, has been identified in Drosophila melanogaster. The SUUR protein lacks homologs by a BLAST search, and only moderate homology is observed between its N-terminal end and chromatin-remodeling proteins of the SWI2/SNF2 family. The gene and the protein were analyzed in insects. Orthologs of the SuUR gene were found in all annotated Drosophila species. The number of amino acid substitutions in the SUUR protein proved to be extremely high, corresponding to that of rapidly evolving genes. Orthologs with low homology were found in mosquitoes Anopheles gambiae, Aedes aegypti, and Culex quinquefasciatus. No orthologs of the SuUR gene were detected beyond Diptera.
DOI
Related Publication(s)
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Associated Information
Comments
Associated Files
Other Information
Secondary IDs
Language of Publication	Russian
Additional Languages of Abstract	English
Also Published As
Research paper	Phylogenetic analysis of the fast-evolving SuUR gene in insects. Yurlova et al., 2010, Russ. J. Genet. 46(9): 1127--1129 [FBrf0218781]
Parent Publication
Publication Type	Journal
Abbreviation	Genetika, Moscow
Title	Genetika
Publication Year	1965-
ISBN/ISSN	0016-6758
Data from Reference
Genes (1)
	SuUR