Reference Report
| Reference | |||
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| Citation | Nicolaï, L.J., Ramaekers, A., Raemaekers, T., Drozdzecki, A., Mauss, A.S., Yan, J., Landgraf, M., Annaert, W., Hassan, B.A. (2010). Genetically encoded dendritic marker sheds light on neuronal connectivity in Drosophila. Proc. Natl. Acad. Sci. U.S.A. 107(47): 20553--20558. (Export to RIS) | ||
| FlyBase ID | FBrf0212380 | ||
| Publication Type | Research paper | ||
| PubMed ID | 21059961 | ||
| PubMed Abstract | In recent years, Drosophila melanogaster has emerged as a powerful model for neuronal circuit development, pathology, and function. A major impediment to these studies has been the lack of a genetically encoded, specific, universal, and phenotypically neutral marker of the somatodendritic compartment. We have developed such a marker and show that it is effective and specific in all neuronal populations tested in the peripheral and central nervous system. The marker, which we name DenMark (Dendritic Marker), is a hybrid protein of the mouse protein ICAM5/Telencephalin and the red fluorescent protein mCherry. We show that DenMark is a powerful tool for revealing novel aspects of the neuroanatomy of developing dendrites, identifying previously unknown dendritic arbors, and elucidating neuronal connectivity. | ||
| DOI | 10.1073/pnas.1010198107 | ||
| Related Publication(s) | |||
| Supplementary material | Supporting Information. [FBrf0212742] |
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| Personal communication to FlyBase | P{UAS-DenMark} insertions. Hassen, 2010.12.22, P{UAS-DenMark} insertions. [FBrf0212859] |
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| All updates | Click here to see a list of all updates to this record from FB2010_08 and on. | ||
Associated Information
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| Secondary IDs | |||
| Language of Publication | English | ||
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Parent Publication
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| Publication Type | Journal | ||
| Abbreviation | Proc. Natl. Acad. Sci. U.S.A. | ||
| Title | Proceedings of the National Academy of Sciences of the United States of America | ||
| Publication Year | 1915- | ||
| ISBN/ISSN | 0027-8424 | ||
Data from Reference
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Alleles (12)
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Constructs (7)
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Genes (7)
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Insertions (3)
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Recent Updates