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Citation
Kuranaga, E. (2011). Caspase signaling in animal development.  Dev. Growth Differ. 53(2): 137--148.
FlyBase ID
FBrf0213046
Publication Type
Review
Abstract

The caspases are a family of cysteine proteases that function as central regulators of cell death. Recent investigations in Caenorhabditis elegans, Drosophila, and mice indicate that caspases are essential not only in controlling the number of cells involved in sculpting or deleting structures in developing animals, but also in dynamic cell processes such as cell-fate determination, compensatory proliferation of neighboring cells, and actin cytoskeleton reorganization, in a non-apoptotic context during development. This review focuses primarily on caspase functions involving their enzymatic activity.

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    Language of Publication
    English
    Additional Languages of Abstract
    Parent Publication
    Publication Type
    Journal
    Abbreviation
    Dev. Growth Differ.
    Title
    Development, Growth and Differentiation
    Publication Year
    1969-
    ISBN/ISSN
    0012-1592
    Data From Reference