A Database of Drosophila Genes & Genomes

FB2013_03, released May 7th, 2013
 

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Citation Zimek, A., Weber, K. (2011). Flanking genes of an essential gene give information about the evolution of metazoa.  Europ. J. Cell Biol. 90(4): 356--364. (Export to RIS)
FlyBase ID FBrf0213069
Publication Type Research paper
PubMed ID 21163549
PubMed Abstract We collected as much information as possible on new lamin genes and their flanking genes. The number of lamin genes varies from 1 to 4 depending more or less on the phylogenetic position of the species. Strong genome drift is recognised by fewer and unusually placed introns and a change in flanking genes. This applies to the nematode Caenorhabditis elegans, the insect Drosophila melanogaster, the urochordate Ciona intestinalis, the annelid Capitella teleta and the planaria Schmidtea mediterranea. In contrast stable genomes show astonishing conservation of the flanking genes. These are identical in the sea anemone Nematostella vectensis and the cephalochordate Branchiostoma floridae lamin B1 gene. Even in the lamin B1 genes from Xenopus tropicalis and man one of the flanking genes is conserved. Finally our analysis forms the basis for a molecular analysis of metazoan phylogeny.
DOI 10.1016/j.ejcb.2010.10.005
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Language of Publication English
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Publication Type Journal
Abbreviation Europ. J. Cell Biol.
Title European Journal of Cell Biology
Publication Year 1979-
ISBN/ISSN 0171-9335
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